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| Registros recuperados: 46 | |
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| Almeida,Ivete Aparecida Zago Castanheira de; Peresi,Jacqueline Tanury Macruz; Alves,Elisabete Cardiga; Marques,Denise Fusco; Teixeira,Inara Siqueira de Carvalho; Silva,Sonia Izaura de Lima e; Pigon,Sandra Regina Ferrari; Tiba,Monique Ribeiro; Fernandes,Sueli Aparecida. |
| Objectives: The aim of this study is to report the occurrence of the first outbreak of food poisoning caused by SalmonellaAlachua in Brazil, as well as the antimicrobial susceptibility and the genetic relatedness of SalmonellaAlachua strains isolated from clinical and food samples.Material and methods: To elucidate the outbreak, an epidemiological investigation was carried out, and two samples of common food were tested - mayonnaise salad and galinhada(a traditional Brazilian dish of chicken and rice) - according to the Compendium of methods for the microbiological examination of foods. Five stool samples were tested employing classic methods for the isolation and identification of enterobacteria. Strains of Salmonella were characterized for antibiotic... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Foodborne diseases; SalmonellaAlachua; Drug resistance; Brazil. |
| Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702015000300233 |
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| Alvares,Jackelline Rodrigues; Mantese,Orlando Cesar; Paula,Alan de; Wolkers,Paula Carolina Bejo; Almeida,Viviene Vieira Prado; Almeida,Samanta Cristine Grassi; Guerra,Maria Luiza Leopoldo Silva; Brandileone,Maria Cristina de Cunto. |
| OBJECTIVES: To determine the prevalence of pneumococcal serotypes and antimicrobial susceptibility in patients with meningitis, and to evaluate the implications for vaccine coverage. METHODS: Pneumococcal strains obtained from normally sterile fluids from patients admitted with meningitis were isolated at the Hospital de Clínicas of the Universidade Federal de Uberlândia, Minas Gerais State, and sent to the Instituto Adolfo Lutz, city of São Paulo, São Paulo State, for further identification, serotyping, and antimicrobial susceptibility determination. RESULTS: From April 1999 to April 2009, 338 pneumococcal strains were isolated, and 72 obtained from patients with meningitis, were analyzed. Patients' ages varied from one month to 82.2 years (mean of 18.4 ±... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Streptococcus pneumoniae; Meningitis; Serotyping; Pneumococcal vaccines; Drug resistance. |
| Ano: 2011 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702011000100005 |
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| Araujo,Orlei Ribeiro de; Silva,Dafne Cardoso Bourguignon da; Diegues,Ana Regina; Arkader,Ronaldo; Cabral,Eloíza Aparecida Ferreira; Afonso,Marta Rodriguez; Louzada,Maria Eduarda; Albertoni,Andréa de Cássia Stéfano. |
| Antibiotic restriction can be useful in maintaining bacterial susceptibility. The objective of this study was verify if restriction of cefepime, the most frequently used cephalosporin in our neonatal intensive care unit (NICU), would ameliorate broad-spectrum susceptibility of Gram-negative isolates. Nine hundred and ninety-five premature and term newborns were divided into 3 cohorts, according to the prevalence of cefepime use in the unit: Group 1 (n=396) comprised patients admitted from January 2002 to December 2003, period in which cefepime was the most used broad-spectrum antibiotic. Patients in Group 2 (n=349) were admitted when piperacillin/tazobactam replaced cefepime (January to December 2004) and in Group 3 (n=250) when cefepime was reintroduced... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Drug resistance; Infection control; Cefepime; Bacterial. |
| Ano: 2007 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702007000200022 |
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| Bashir,Saira; Sarwar,Yasra; Ali,Aamir; Mohsin,Mashkoor; Saeed,Muhammad Azeem; Tariq,Ayesha; Haque,Abdul. |
| The objective of this work was the phylogenetic characterization of local clinical isolates of uropathogenic E. coli with respect to drug resistance. A total of 59 uropathogenic E. coli responsible for community acquired urinary tract infections were included in this study. A triplex PCR was employed to segregate each isolate into four different phylogenetic groups (A, B1, B2 and D). Drug resistance was evaluated by disc diffusion method. The drugs used were ampicillin, aztreonam, cefixime, cefoperazone, ceftriaxone, cephradine among β-lactam group; amikacin, gentamicin, and streptomycin among aminoglycosides; nalidixic acid and ciprofloxacin from quinolones; trimethoprim-sulfomethoxazole, and tetracycline. Among 59 uropathogenic E. coli isolates majority... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Uropathogenic E. coli; Phylogenetic analysis; Drug resistance. |
| Ano: 2011 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822011000400005 |
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| Carmona,F.; Prado,S.I.; Silva,M.F.I.; Gaspar,G.G.; Bellissimo-Rodrigues,F.; Martinez,R.; Matsuno,A.K.; Carlotti,A.P.C.P.. |
| The objective of this study is to retrospectively report the results of interventions for controlling a vancomycin-resistant enterococcus (VRE) outbreak in a tertiary-care pediatric intensive care unit (PICU) of a University Hospital. After identification of the outbreak, interventions were made at the following levels: patient care, microbiological surveillance, and medical and nursing staff training. Data were collected from computer-based databases and from the electronic prescription system. Vancomycin use progressively increased after March 2008, peaking in August 2009. Five cases of VRE infection were identified, with 3 deaths. After the interventions, we noted a significant reduction in vancomycin prescription and use (75% reduction), and the last... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Infections; Antibiotics misuse; Drug resistance; Vancomycin-resistant enterococcus. |
| Ano: 2012 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2012000200011 |
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| Cortes,Jorge Alberto; Leal,Aura Lucía; Montañez,Anita María; Buitrago,Giancarlo; Castillo,Juan Sebastián; Guzman,Lucy. |
| OBJECTIVE: The aim of this study was to describe the most frequently found bacterial microorganisms in bloodstream isolates taken from patients in intensive care units in Colombia and their resistance profiles. METHODS: This was a multicentre descriptive observational study that was carried out between January 2001 and June 2008 with laboratory data from 33 participating hospitals in a surveillance network. RESULTS: The most frequently found microorganisms were coagulase-negative Staphylococci 39.6%, Staphylococcus aureus 12.3%, Klebsiella pneumoniae 8.2%, Escherichia coli 5.7%, Acinetobacter baumannii, 4.0% and Pseudomonas aeruginosa 3.8%. Coagulase-negative Staphylococci registered greater than 70% oxacillin resistance rate. S. aureus presented a change... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Bacteremia; Intensive care unit; Drug resistance; Anti-bacterial agents; Colombia/epidemiology; Epidemiologic surveillance. |
| Ano: 2013 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702013000300007 |
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| De Oliveira-júnior, Raimundo Gonçalves; Nicolau, Elodie; Bonnet, Antoine; Prunier, Grégoire; Beaugeard, Laureen; Joguet, Nicolas; Thiéry, Valérie; Picot, Laurent. |
| Melanoma is an aggressive tumor with invasive and metastatic potential, frequently exhibiting multidrug resistance mechanisms. In our continuous search for antimelanoma molecules, we have identified some effective marine compounds capable of not only inducing cell death, but also of sensitizing chemoresistant tumor cells to clinically used anticancer drugs. In this report, the cryptophyte Rhodomonas salina (Wislouch) D.R.A.Hill & R.Wetherbee, Pyrenomonadaceae, was chemically investigated in order to identify pigments efficiently inhibiting melanoma cells proliferation. All pharmacological tests were performed on A2058 cells expressing the oncogenic BRAF V600E mutation and resistant to dacarbazine treatment. Flash chromatography of R. salina ethanol... |
| Tipo: Text |
Palavras-chave: Alloxanthin; Chemosensitivity; Crocoxanthin; Cutaneous melanoma; Drug resistance; Microalgae. |
| Ano: 2020 |
URL: https://archimer.ifremer.fr/doc/00630/74194/73918.pdf |
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| França,P.H.C.; Coelho,H.S.M.; Brandão,C.E.; Segadas,J.A.; Quintaes,R.F.; Carrilho,F.J.; Ono-Nita,S.; Mattos,A.A.; Tovo,C.; Gouvea,V.S.; Sablon,E.; Vanderborght,B.O.M.. |
| Given the loss of therapeutic efficacy associated with the development of resistance to lamivudine (LMV) and the availability of new alternative treatments for chronic hepatitis B patients, early detection of viral genotypic resistance could allow the clinician to consider therapy modification before viral breakthrough and biochemical relapse occur. To this end, 28 LMV-treated patients (44 ± 12 years; 24 men), on their first therapy schedule, were monitored monthly at four Brazilian centers for the emergence of drug resistance using the reverse hybridization-based INNO-LiPA HBV DR assay and occasionally sequencing (two cases). Positive viral responses (HBV DNA clearance) after 6, 12, and 18 months of therapy were achieved by 57, 68, and 53% of patients,... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Hepatitis B; Antiviral therapy; Lamivudine; Drug resistance; YMDD variants; Hepatitis B virus. |
| Ano: 2007 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2007001200003 |
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| Gárcia,Carlos M.B.; Sprenger,Lew K.; Ortiz,Efraín B.; Molento,Marcelo B.. |
| This study aimed to report the presence of parasites resistant to the most used anthelmintic drugs in sheep in Colombia. Four farms (denominated farm 1, 2, 3 and 4) were selected where the animals were not treated with anthelmintics for two months before the trial. Animals with faecal egg count (FEC) above 150 and of different ages were allocated into six groups, each consisting of at least 5 animals. The drugs and dosages used were: ivermectin 1% (0.2 mg/kg), albendazole 25% (5 mg/kg), fenbendazole 10% (5 mg/kg), levamisole 10% (5 mg/kg), and moxidectin 1% (0.2 mg/kg). Anthelmintic efficacy was determined by the FEC reduction test (FECRT) with a second sampling 14 days post-treatment. The efficacy of albendazole and fenbendazole at farm 1 was above 95%,... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Drug resistance; EPG; FECRT; Helminth. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652016000100397 |
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| Gatesoupe, Joel. |
| Formaldehyde was used to disinfect Artemia cysts and nauplii, while introducing two probiotics in the enrichment process: Bactocell (Pediococcus acidilactici) and Levucell (Saccharomyces cerevisiae). The disinfectant was selected due to its potential compatibility with probiotics, since it was more effective against Gram-negative bacteria than against lactic acid bacteria and yeast. However, the presence of formaldehyde reduced the intake of P. acidilactici in Artemia. Consequently, the disinfection was stopped before Bactocell supplementation to the nauplii fed to pollack (Pollachius pollachius) larvae. The mean weight of pollack was higher with this probiotic treatment. Growth was even better with the combination of Levucell and Bactocell, but the yeast... |
| Tipo: Text |
Palavras-chave: Drug resistance; Bacterial genotype; Disinfection; Probiotic; Artemia; Marine fish larvae. |
| Ano: 2002 |
URL: http://archimer.ifremer.fr/doc/2002/publication-393.pdf |
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| Iguchi, Aiko; Soma, Takehisa; Suzuki, Hiroshi; Xuan, Xuenan. |
| In 73 gDNA samples from Babesia gibsoni-infected dogs, the M121I variant population was measured by using allele-specific real-time PCR. Although the mechanism of atovaquone against B. gibsoni has not been clearly identified, it is reported that the mitochondria cytochrome b gene of the atovaquone-resistant B. gibsoni had a single-nucleotide substitution at nt363 (G to T), which resulted in the substitution of methionine with isoleucine (M121I). In this study, 3/73 samples showed over 5% M121I variant population. Although the M121I variant population is a low percentage, it runs the risk of spreading drug-resistant parasites. It is important to prevent the spread of drug-resistance, so we need to gather information about this at regular intervals. |
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Palavras-chave: Allele-specific real-time PCR; Babesia gibsoni; Drug resistance; M121I variant population. |
| Ano: 2016 |
URL: http://ir.obihiro.ac.jp/dspace/handle/10322/4421 |
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| Registros recuperados: 46 | |
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